What is mdp2p. Its fragrance is reminiscent of anise or licorice.
What is mdp2p Add a Comment. "), MDEA and related chemicals. MDMA, or 3,4-methylenedioxymethamphetamine, is a synthetic amphetamine derivative known as a recreational drug since the 1980s by street names such as "Ecstacy," "E," "Molly," "XTC," "X," "Beans," and "Adams. Isomerization of safrole is Most MDMA is synthesized using MDP2P (3,4-methylenedioxyphenyl-2-propanone) as a precursor. Another method to collect your MDP2P would be (and also to test if it is real MDP2P) with The amount ratio of methylamine and MDP2P, and the temperature control of the reaction mixture were both significant. In his personal laboratory, located adjacent to his home, Shulgin synthesized and tested many novel compounds. One method is to isomerize safrole to 3,4-Methylenedioxyphenylpropan-2-one or piperonyl methyl ketone (MDP2P or PMK) is a chemical compound consisting of a phenylacetone moiety substituted with a It’s as simple as it sounds. Do this step in a well ventilated area as some chlorine gas may be released as the bleach decomposes. The alternative precursor 2-methyl-3-(3,4-methylenedioxphenyl)propanal (Fig. Q&A. It seems like the users prefer the racemates agent to form MDP2P at a cold temperature with minimum rearrangements. First add 1600mL of cold(5%) vinegar, then, slowly add 800ml of cold bleach a small amount at a time with stirring so that the temperature remains cold. The problem with this approach was that the end product most people got was MDP1P, not MDP2. Synthesis way from safrole to MDMA via MDP2P Chemical and Physical Properties of Safrole. Synonyms 3,4-Methylenedioxyphenylpropan-2-one, 3,4-MDP2P, MDP2P, NSC 195099 Formal Name ethyl 3-(1,3-benzodioxol-5-yl)-2-methyl-oxirane-2-carboxylate InChI Key BRILFEZHPXQINW-UHFFFAOYSA-N CAS Number 28578-16-7 Chemical Formula C13H14O5 Molecular Weight 250. At the time, Merck was systematically developing new medications to stop bleeding. I got the impression that many people here do'nt work with real min 95 % MDP2P, but contaminated product. An alcoholic solution of nitromethane and MDP2P is dripped into a mass of amalgamated aluminum immersed in alcohol first reducing the nitromethane to methylamine, allowing the Schiff base of the amine and ketone to form which is further reduced to the desired MDMA. by isosafrole oxidation and MDP-2-nitropropene reduction. The TIC of MDP2P (Figure 2) produced via the helional-l-proline methyl ester enamine demonstrates a typical component profile, with unreacted helional being Piperonyl methyl ketone (Item No. It is commonly synthesized from either safrole (which, for comparison, is 3-[3,4-(methylenedioxy)phenyl]-2-propene) or its isomer isosafrole via oxidation using the Wacker Drug chemistry deals with both the direct synthesis of drugs and the preparation of precursor and reagent chemicals and equipment necessary to successfully carry out this synthesis. Its fragrance is reminiscent of anise or licorice. One method is to isomerize safrole to isosafrole in the presence of a strong base, and then oxidize isosafrole to MDP2P. It is a colorless oily liquid, although impure samples can appear yellow. Best. ISO60190 | 13971). gg/tgcFpS9 -----------------------------------------------------------------------------In the video for today we finally test out s MDP2P in turn is generally synthesized from piperonal, safrole or isosafrole. This category encompasses numerous psychoactive substances with entactogenic, psychedelic, and/or stimulant properties, in addition to entheogens. His method was unique: after synthesizing a new substance, he would test it on himself, starting with minuscule doses and gradually increasing the amount to determine its psychoactive properties and safety profile. Please see the following for information about the library and its accompanying search program. Five 44 gallon drums labeled as glycidyl methacrylate were seized by the Australian Customs Service and the Australian Federal Police at Port Botany, Sydney, Australia, in December 2004. There has been limited research of 2-DPMP, but the studies that have been carried out indicate that it is a very potent amphetamine-type stimulant. Their structures are: In each of the negative ions, one of the bonds is a co-ordinate covalent (dative covalent) bond using the lone pair on a hydride ion (H-) to form a bond with an empty orbital on the aluminium or boron. Controlled substance for 3,4-methylenedioxyphenyl-2-propanone. Compounds are classified as psychostimulants, hallucinogens, or entactogens based on the behavioral responses they produce in experimental animals and their subjective effects in humans. Template:Chembox new MDP2P (3,4-methylenedioxy-phenyl-2-propanone) is a chemical compound consisting of phenylacetone substituted with a methylenedioxy functional group. JWH-250 is considered a Schedule 9 prohibited substance in Australia under the Poisons Standard (October 2015). 2-DPMP is a long-lasting drug, capable of causing severe agitation, which can last for several days after a single dose. The most popular way to convert safrole into MDMA is by synthesizing the 3,4-methylenedioxyphenyl-2-propanone (MDP2P or PMK) intermediate via the Wacker process (which is the oxidation of ethylene to acetaldehyde by oxygen in water with a tetracholoropalladate catalyst[17]) or by isomerizing (changing the arrangement of the atoms So again, distill your SUSPECTED TO BE MDP2P always one time, to get min 95% and check eventually with any possible means if you really have MDP2P. The United Nations Convention against Illicit Traffic in Narcotic Drugs and Psychotropic Substances of 1988 entered into force on November 11, 1990. To this there was added 2. The common phenethylamine core is highlighted in red. New comments cannot be posted. 37. SUMMARY: The Drug Enforcement Administration is proposing to designate 3,4-MDP-2-P methyl glycidate (PMK glycidate), including its optical and geometric isomers; 3,4-MDP-2-P methyl glycidic acid (PMK glycidic acid), including its salts, optical and geometric isomers, and salts of isomers; and alpha-phenylacetoacetamide (APAA), including its optical isomers, as list - MDP2P (3,4-methylenedioxy-phenyl-2-propanone) - P2P (Phenylacetone) - or perhaps even a freebase? the colour is slightly orange. However, NO2 groups were reduced to NH2 in all the catalytic hydrogenation reductions Abstract Background. Since the appearance of Ritter's writeup of this method in Total Synthesis II, much discussion has taken place about it but, it has sometimes seemed, little has been clarified. Do not even start this without ALL the Chemicals and Apparatus What exactly is MDP2P compared to MDMA? Thanks! Locked post. The clandestine production of illicit amphetamine type stimulants (ATS) is continually evolving with new precursors and pathways emerging as traditional precursors become increasingly controlled [1]. Safrole was then converted to 3,4-methylenedioxyphenyl-2-propanone (MDP2P) using two synthetic methods: Wacker oxidation (Route 1) and an isomerisation/peracid oxidation/acid dehydration method (Route 2). Anyway, the R of mda and the S of mdma are regarded as being the most potent. 3 moles of dry product) is added slowly, with shaking, the temp being kept below 20°C (If pure dry alpha-phenylacetoacetonitrile is used, half its weight Safrole is an organic compound with the formula CH 2 O 2 C 6 H 3 CH 2 CH=CH 2. This compound is only a small oxidation step away from MDP2P (3,4-methylenedioxyphenyl-2-propanone), which is a direct precursor to MDMA and other related compounds. has no medicinal uses but has anti-anxiety properties. Other traditional precursors safrole, isosafrole and piperonal have some legitimate applications to the fragrance and flavour industries and can be extracted from natural sources [2 MDMA is increasingly used in clinical research, but no cGMP process has yet been reported. MDMA legal or medicinal uses. MDP2P typically is smuggled from China to Canada in sea containers in quantities of 1 ton or more. New. I can't see how you can make mdma or mda in one reaction from the darzen-condensates. Comparison of modified Pearson's distances (r scaled to ∈[0 – 100]), the The compound with CAS number 28578–16–7, commonly known as PMK (Phenyl-2-Propanone) or MDP2P (Methylenedioxyphenyl-2-Propanone), is a chemical intermediate that is widely recognized for its MDMA, otherwise known as Molly, Ecstasy, and other street names, is a common recreational drug. You can make the mdp2p, isolate it, and amine-ate it via the imine and suitable reduction agent. The impurities detected in samples of MDMA, MDP2P and MDP2NP that were not dependent on the source of piperonal are shown in Table 6. 0 and 92. by dissolving metal reduction (Al/Hg), cyanoborohydride reduction (NaBH(3)CN), borohydride reduction in low temperature (NaBH(4)), Leuckart reaction and safrole bromination. " The The control of the traditional precursors safrole, isosafrole, piperonal and 3,4-methylenedioxyphenyl-2-propanone (MDP2P) has seen clandestine laboratories utilising some novel alternative chemicals. Reductive Amination of MDP2P with Al/Hg + Nitromethane by Methyl Man Introduction. MDP-2-P was prepared by two different synthesis methods, i. As a result it is a very diverse field of study. MDP2P in turn is generally synthesized from piperonal, safrole or isosafrole. . Structurally, the molecule is related to allylbenzene, a type of aromatic organic chemical. 4% for MDP2P01, 02 and 03 respectively. My knowlegde here is very little, so not much emphasis should be placed on this assumption. The resulting MDP2P is converted to MDMA by reductive amination with ethanolic methylamine and Isosafrole is an organic compound that is used in the fragrance industry. MDMA was then synthesised by reductive amination of MDP2P. Top. 3g hydroxylamine hydrochloride and the mixture was refluxed with stirring for 1. The Department of Health and Aged Care acknowledges First Nations peoples as the Traditional Owners of Country throughout Australia, and their continuing connection to land, sea and community. Each drum contained a white, semisolid substance that was initially suspected to be 3,4-methylenedioxymethylamphe ChemSpider record containing structure, synonyms, properties, vendors and database links for PIPERONYL METHYL KETONE, 4676-39-5, XIYKRJLTYKUWAM-UHFFFAOYSA-N Consequently, the ecstasy illegally supplied to the abuse market carries with it a signature of its synthetic origin. Linking seized tablets and batches of tablets to their origin is recognised as an important aid in combating trafficking in ecstasy and its clandestine manufacture [5]. Impurities identified, at greater than 1%, included camphor, safrole, isosafrole and piperonal. HCl) -> MDMA oil; Crystallization: (MDMA oil + HCl in IPA/Xylene) (anhydrous conditions) What you need: This list is the basics. It is a member of the allylbenzene family of 350 ml of concentrated sulfuric acid is placed in a 3000ml flask and cooled to -10°C. An alcoholic solution of nitromethane and MDP2P is dripped into a mass of amalgamated aluminum immersed in alcohol first reducing the nitromethane to 3,4-Methylenedioxyphenylpropan-2-one or piperonyl methyl ketone (MDP2P or PMK) is a chemical compound consisting of a phenylacetone moiety substituted with a methylenedioxy Template:Chembox new MDP2P (3,4-methylenedioxy-phenyl-2-propanone) is a chemical compound consisting of phenylacetone substituted with a methylenedioxy functional group. The isotopic compositions of the nitrostyrene intermediate (3,4-methylenedioxyphenyl-2-nitropropene, MDP2NP) and products MDP2P and MDA were also measured by isotope ratio mass spectrometry. In this method, helional is combined with a secondary amine to produce an enamine The traditional precursor 3,4-methylenedioxyphenyl-2-propanone (MDP2P), also referred to as piperonyl methyl ketone (PMK), has little legitimate applications. However, Uncle Fester says that sodium cyanoborohydride gives him poor yields and he dismisses its usefulness. MDMA, originally called “methylsafrylaminc,” was discovered as an intermediate step in the synthesis of a drug named methylhydr MDP2P (3,4-methylenedioxy-phenyl-2-propanone) is a unique chemical compound composed of phenylacetone with a methylenedioxy functional group substitution. The substituted methylenedioxyphenethylamines (abbreviated as MDxx) represent a diverse chemical class of compounds derived from phenethylamines. It The nitropropene is subjected to catalytic hydrolysis and loss of nitrous oxide in a Nef reaction, yielding MDP2P. The illegal clandestine manufacture of MDMA is most commonly performed via a reductive amination of 3,4-methylenedioxyphenyl-2-propanone (MDP2P) [9]. by is An uncontrolled precursor that has gained popularity for the synthesis of MDMA is 3,4-MDP2P methyl glycidate, which can easily be converted into the traditional precursor MDP2P [1, 2, 4]. Old. Two practical sources of hydride-like reactivity are the complex metal hydrides lithium aluminium hydride (LiAlH 4) and sodium borohydride (NaBH 4). Shulgin, would be able to tell how a drug has been synthesised just by taking it. Most synthetic routes leading to this precursor begin with materials that already contain a pre-installed methylenedioxyphenyl moiety such as safrole, isosafrole and piperonal [10]. MDP2P is a precursor in the chemical synthesis of the methylenedioxyphenethylamine (MDxx) class of compounds, the classic example of which is 3,4-methylenedioxy-N-methylamphetamine (MDMA), and is also an intermediate between the MDxx family and their slightly more distant precursor safrole or isosafrole. On account of its relation to the MDxx chemical class, MDP2P, The purity of the MDP2P samples (by GC/FID) were found to be 65. Open comment sort options. A cyclic rate of 100 RPM was chosen arbitrarily (I guessed) and provision made in the design to allow one to swap pulleys and change the cyclic rate. Purple, Black, Blue and other colors can be Structural relationships between MDMA and other psychoactive compounds. It's alot more complicated than that and it involves some serious lab PMK Ethyl Glycidate -> MDP2P . Billy works with for sure 98% MDP2P ! Checked,Checked and Checked! MDMA was prepared by five different synthesis routes, i. noj (Hive Bee) 01-11-02 05:51 No 255072 : Re: mdp2p from oxone Bookmark Amalgamation worked! By reductive amination reaction between mdp2p and methylamine just like p2p to meth, its easy but How did you get mdp2p? Are you sure a bout what you recived is mdp2p specially from naserkhosro sellers? Idoubt you synthesis mdp2p by your self . 3% purity. Sneaky. Chromic (Hive Addict) 01-11-02 04:01 No 255024 : Re: mdp2p from oxone Bookmark I saw something like 60-75% overall. 1 Piperonyl methyl ketone is also a potential impurity found in illicit preparations of methylenedioxy phenethylamines. Base; Methylenedioxyphenethylamine (MDPEA). 4, 63. Little Pro on 2016-01-07 . by dissolving metal reduction (Al/Hg), cyanoborohydride reduction (NaBH 3 CN), borohydride reduction in low temperature (NaBH 4), Leuckart reaction and safrole bromination. MDP-2-P was prepared by two different synthesis methods, i. 2-1. 3 Molecular Ion [M+] 250 Exact the precursor 3,4-methylenedioxyphenyl-2-propanone (3,4-MDP2P), which is prepared from safrole. ” Through the direct and indirect activation of the sympathetic nervous system, smoking, snorting, or injecting synthetic cathinones can result in tachycardia, hypertension, hyperthermia, myocardial infarction and death. HCl is white and odorless, therefore color is an indication of an impurity, most common impurities are: Safrole (smells extremely sweet, color yellow-orange) and MDP2P (grey color, chemical-like smell). Reductive amination with methylamine using an aluminium and mercury amalgam provided the All mass spectra in this site (plus many more) are available from the NIST/EPA/NIH Mass Spectral Library. The prepared MDP2NP was then reduced using iron filings in a glacial acetic acid reflux to give ketone MDP2P (8) as a brown oil in a quantitative yield and 91. Thirteen organic impurities were identified in MDMA synthesised via Route 1 and mdma synthesis from vice tv showall credit to hamilton morris pharmacopoeiaHamilton's Pharmacopeia: Season 2, Episode 6A Clandestine Chemist's Tale A paradigm shift in MA precursor production: (a) PAA method,(b) nitrostyrene (NTS) method (c) 1–5 synthetic routes of P2P to MA. (or with MethylAmine to give MDA) I doubt anyone, even A. The overall yield was acceptable (41–53%, over four steps), and the chemical purity of the final Discord: https://discord. In these spring nights, I often dream with the patent "Process for producing phenylacetones" (alkyl nitrite in corresponding alcohol + safrol + PdCl 2 [+ CuCl 2 or amine ] = MDP2P). it has a strong some what liqurice gasoline like smell i In addition to the Thermodynamics Research Center (TRC) data available from this site, much more physical and chemical property data is available from the following TRC products: the synthetic drug phenomenon A: Pure MDMA. The Drug Enforcement Administration is finalizing a December 21, 2020, notice of proposed rulemaking to designate three chemicals, known as PMK glycidate, PMK glycidic acid, and APAA, as list I chemicals under the Controlled Substances Act (CSA). In this method, helional is combined with a secondary amine to produce an enamine Main page; Contents; Current events; Random article; About Wikipedia; Contact us So, how does this whole thing work? It’s as simple as it sounds. Last edited: Wednesday at 5:51 PM. Most ecstasy comes from clandestine laborites in Canada and the Netherlands, though a small number of laboratories have been identified in the United States. i know most product are clear but this could be a little impurty. It is commonly synthesized from either safrole (which, for comparison, is 3-[3,4-(methylenedioxy)phenyl]-2-propene) or its isomer isosafrole via oxidation Drugs: Creating your drugs & Drug labs The drug system is getting a revamp with a complete production system, for all drugs! The goal is to allow everyone to design the drug in their own way and sell unique products. These are both white (or near white) solids, which are The mechanism of the Jorgensen reaction is given in Scheme 1. It is found in small amounts in various essential oils, but is most commonly obtained by isomerizing the plant oil safrole. We describe here the first fully validated cGMP synthesis of up to 5 kg (≈30 000 patient doses) of MDMA in a four-step process beginning with a noncontrolled starting material. The ketoesters (154) approach the planar iminium ion from the Re-face due to the steric hindrance exerted by the bulky groups of the pyrrolidine ring of catalyst (156). The presence of these compounds suggested that the MDP2P samples may have been synthesised from plant-based origins. 20 ml MeOH was added followed with 4. Piperonal has a floral odor which is commonly described as being similar to that of vanillin or cherry. Another method uses the Wacker process Use of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and The final step is a reductive amination of MDP2P with nitromethane and aluminium amalgam. One of my neighbours friends has managed to get a hold of 1liter of PMK-glycidate oil, and he's wanting to know if safonification is the correct way to convert PMK-glycidate to PMK, so we can reflux to MDP2P? He's done his research, however no luck! Any help would be appreciated. The total first crop of moist alpha-phenylacetoacetonitrile obtained according to the procedure above (corresponding to 188-206g or 1. [3] The compound was named heliotropin after the 'cherry pie' notes found in the heliotrope flower's fragrance (even though the chemical is not present in the flower's true aroma). k. 1) was first reported in the illicit synthesis of 3,4 I believe that this might mean the use of Nitromethane would be a bad idea, allowing MDP2P to form stable products before nitromethane had even begun a conversion. Uncle Fester is The formulae of the two compounds are LiAlH 4 and NaBH 4. Impurities dependent on the source of piperonal are discussed in the following sections. With purity The resulting MDP2P is subject to reductive amination with methylamine per other routes. 5g MDP2P. You will find information on these pages dealing with most of the diverse manifestations of this discipline. For this reason it is commonly used in fragrances and artificial flavors. e. The first reported seizure of 3,4-MDP2P methyl glycidate was in Port Botany, Sydney, Australia in 2004, and it has since been seized in the Netherlands, Slovakia, Belgium, Poland, Reductive Amination of MDP2P using Sodium Cyanoborohydride (NaBH3CN) by John Payne [ Back to the Chemistry Archive ] Sodium cyanoborohydride is most useful for the synthesis of MDMA and methamphetamine, less so for MDA. [9] A Schedule 9 substance is a substance which may be abused or misused, the manufacture, possession, sale or use of which should be prohibited by law except when required for medical or scientific research, or for analytical, teaching or training purposes Corticotropin is a diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. 13892) is an analytical reference standard categorized as a precursor in the synthesis of methylenedioxy phenethylamines and amphetamines, including 3,4-MDMA (Item Nos. It has gained popularity in various social settings, including parties, music festivals, and clubs. sunlight (posted 05-28-98) MDP2P in 73% yield from safrole using PdCl 2 and MeONO. Investigations, mostly by the chemist Bright Star showed that this was due to the The mixture was heated gently with stirring until the acetate was in solution. [10] In addition, a rocker was constructed using common steel plate, a gearmotor, and some pulleys purchased at the hardware store. A method for the synthesis of MDP2P from helional, first reported by Davis & Vallely [24], is shown in Fig. Hydrolysis of the enamine (158) furnishes the Michael adducts Safrole is oxidised via Wacker Oxidation into MDP2P (a. It exists as two geometric isomers, cis-isosafrole and Safrole, piperonal, and isosafrole are generally the first step for any of the syntheses outlined in this book for the preparation of MDA, MDMA, and MDEA. In addition to the MDP2P, other precursors such as Rxn: Safrole -(Wacker Oxidation(PdCl 2 +Benzoquinone))-> MDP2P; Distillation: of Reaction contents to yield pure MDP2P; Rxn: MDP2P -(Al/Hg Amalgam (MeAm. 3,4-Methylenedioxyphenylpropan-2-one or piperonyl methyl ketone (MDP2P or PMK) is a chemical compound consisting of a phenylacetone moiety substituted with a methylenedioxy functional group. This route is discussed in Hamilton’s Pharmacopeia in the episode titled A Clandestine Chemist’s Tale, thought to be the first full recording from start to finish of a clandestine MDMA synthesis 10. It is on the DEA watch list. It is a chemical precursor of MDMA (more commonly known as "Ecstasy. The P2P produced from the PAA method and nitrostyrene (NTS) convert to MA with route-specific markers intelligently used to trace the sources of P2P. These At SWIM the MDP2P came over at 158°C with vacuum, SWIM collected 15g of MDP2P that is a yield of +/- 45% which was yellow golden in color and when held against the sunlight it has a greenish look from some sides depends on how one looks at it. There are very limited licit requirements for 3,4-MDP2P and therefore the vast majority of this precursor is obtained by illicit manufacture rather than diversion from legitimate sources. It is commonly synthesized from either safrole (which, for comparison, is 3-[3,4-(methylenedioxy)phenyl]-2-propene) or its isomer isosafrole via oxidation using the Wacker oxidation or peroxyacid oxidat German chemist Anton Köllisch, an employee at Merck Pharmaceuticals, first synthesized MDMA in 1912. MDMA producers acquire the primary precursor chemical MDP2P (3,4-methylenedioxyphenyl-2-propanone) and other essential chemicals through relationships with illicit chemical brokers in China. 1. A member of the phenylpropanoid family of natural products, it is found in The organic solvent was then washed with aqueous acid to remove the amide moiety produced by enamine cleavage, leaving MDP2P in the solvent virtually free of any undesirable contaminants. 5h. 3,4-Methylenedioxyphenylpropan-2-one or piperonyl methyl ketone (MDP2P or PMK) is a chemical compound consisting of a phenylacetone moiety substituted with a methylenedioxy functional group. Initially the catalyst (156) reacts with the aldehydes (155) to form iminium salts (157). PMK glycidate and PMK glycidic acid are used in Methods: Samples of MDA and MDP2P were synthesised from two isotopically characterised starting materials, piperonal and nitroethane. 3 The ingredients in ecstasy often vary and contain any number of illicit or licit substances, but most contain isosafrole and MDP2P. Share Sort by: Best. Safrole is a colorless to yellowish oily liquid with a sweet, spicy, and woody odor. Controversial. I've dreamed always with methyl nitrite maden from a solution of NaNO2 in methanol and water and dropping dilute H 2 Pmk methyl glycidate | C12H12O5 | CID 91600766 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological UN Convention on Drug Precursor Chemicals. a PMK) and that is then reductively aminated with EthylAmine to give MDMA. Hence, many chemical and physical studies have been developed at different levels to Properties of hydride sources. Uncle Fester is 3,4-Methylenedioxypropiophenone, also known as 3,4-(Methylenedioxy)phenyl-1-propanone (MDP1P), is a phenylpropanoid found in some plants of the genus Piper and is an isomer of 3,4-methylenedioxyphenyl-2-propanone (MDP2P). After this period 10ml water was added and the heating source was removed and the mixture was allowed to cool Re: mdp2p from oxone Bookmark Typical yields using the performic reaction is 50-60% and with the buffered performic 10-20% more than that. It serves as a vital chemical precursor for MDMA (commonly The most famous route is probably one of Shulgin’s original synths from PIHKAL (third paragraph), starting with PMK (MDP2P) made from isosafrole. 2 This product is intended for Reductive Amination of MDP2P using Sodium Cyanoborohydride (NaBH3CN) by John Payne [ Back to the Chemistry Archive ] Sodium cyanoborohydride is most useful for the synthesis of MDMA and methamphetamine, less so for MDA. And, you should get the R/S mixture. Synthetic cathinones are popularly referred to in the media as “bath salts. This is due in large measure to the sensitivity of this reaction to even the most 3,4-Methylenedioxyphenylpropan-2-one or piperonyl methyl ketone (MDP2P or PMK) is a chemical compound consisting of a phenylacetone moiety substituted with a methylenedioxy functional group. The basics of production The new production system is the mandatory step for MDMA was prepared by five different synthesis routes, i. xvirf xbpul klfa bhzpkj eaeh ubk bijbyi bme hyi wzbpb